polio and parkinson

Has anyone looked at the relationship between Bolbar Polio and PD? My husband had Bolbar Polio as a child and was in a iron lung. He was left with a slight swallowing problem which he compensated for. He died because the swallowing became worce with PD resulting in a feeding tube. At the end enen that regurgitated. He was in a clinical trail study at the Tampa movement disorder group.. 2005..and died in 2006… so his records may still be there.. His name was Gerald David Tucker.. thanks for your attention.. joan tucker

Dr. Sanchez-Ramos said...

Dr. Abe Lieberman who has provided answers in this blog for many years was interested in the relationship between polio and development of PD. He wrote in 2009:
“No one has statitstics on the prevlance of post polio and parkinson disease. The majority of people with PD do not have a history of polio or post polio syndrome”.

For more reading on this topic click the link below

http://www.ippso-world.org/ppsinfo/articles/bruno/fatiguetreat.html

Or you can read this excerpt by:
Richard L. Bruno, Ph.D., Nancy M. Frick, Lh.D., Susan J. Creange, M.A., Todd Lewis, Ph.D., and Terry Molzen, M.S

“During the polio epidemics of the 1950′s, there were several small outbreaks of patients having drowsiness, prolonged sleeping, slowing of brain waves, as well as some of the symptoms of both bulbar polio and Parkinson’s disease (e.g., tremor and rigidity). In 1952, Type II poliovirus was isolated from one group of patients having these symptoms and it was found that the neurons in their brain activating system had been damaged”.

“The association of decreased brain activation and Parkinson’s disease symptoms remind Dr. Oliver Sacks of the ‘sleeping sickness’ patients with Parkinson’s disease he described in his book Awakenings.The relationship between ‘sleeping sickness,’ Parkinson’s disease and polio may be important for understanding post-polio fatigue, since all of these have conditions are associated with damage to a part of the brain activating system called the basal ganglia.For example, Parkinson’s disease (PD) patients have severe damage to one of the basal ganglia, the substantia nigra which produces the neurotransmitter dopamine. PD patients often describe fatigue. ‘Excessive fatigue’ was reported by 48% of PD patients in one study while nearly one-third of PD patients reported that fatigue was their ‘most disabling symptom’. As a matter of fact, one of the first descriptions of Parkinson’s disease could serve as a definition of post-polio fatigue, i.e., a syndrome ‘characterized by a diminution of voluntary attention, spontaneous interest, initiative and the capacity for effort and work, with significant and objective fatiguability, and a slight diminution of memory”