Medically reviewed by Heidi Moawad, M.D. — Written by S. Srakocic — Updated on February 9, 2026
Parkinson’s disease is a chronic neurodegenerative condition that causes symptoms such as tremors, muscle stiffness, and speech difficulties. The condition progresses slowly, and symptoms get worse with time.
Symptoms of Parkinson’s can fluctuate throughout the day. For instance, you may feel better at lunchtime than you do in the late evening. But daily variations in the symptoms of Parkinson’s disease are mild, and symptoms don’t resolve completely on their own.
A sudden increase in Parkinson’s symptoms is almost always linked to an underlying cause. This could be something minor, such as a recent medication change, or something potentially serious, such as an infection.
Do Parkinson’s symptoms come and go?
Parkinson’s disease symptoms can fluctuate throughout the day and worsen during certain periods, such as the early morning or late evening. This is typically because medications begin to wear off between doses.
Parkinson’s symptoms get worse over time at a steady, but slow, rate.
Other underlying causes that can worsen Parkinson’s symptoms include:
- stress
- recent medication changes
- recent surgery or other medical procedures
- sleep difficulties
- dehydration
- a new injury or illness
It’s important to let your doctor or healthcare professional know if you notice a sudden change in your Parkinson’s symptoms.
Learn more here: Why Do Parkinson’s Disease Symptoms Come and Go?
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