Cedars-Sinai program shows app may prompt earlier care decisions

Written by Andrea Lobo | March 16, 2026

  • Kneu Health’s smartphone platform enables ongoing monitoring of Parkinson’s symptoms between clinic visits.
  • The app tracks movement, speech, cognitive function, and nonmotor symptoms such as sleep.
  • Clinicians reported the platform helped identify the need for earlier intervention and more personalized care planning.

The integration of Kneu Health’s smartphone-based platform into Cedars-Sinai’s Parkinson’s care program enabled ongoing symptom monitoring and revealed the need for earlier intervention in 79% of encounters.

According to the company, clinicians reported that the added insight helped care teams monitor treatment responses and inform more timely, personalized care adjustments for people with Parkinson’s disease.

The platform was used daily by 104 people with Parkinson’s as part of their routine care. Over six months, it captured more than 46,000 measures of movement, speech, and cognitive function. The results also showed that clinicians reported a deeper understanding of disease progression in 93% of encounters.

Why tracking symptoms between visits is important in Parkinson’s

“As Parkinson’s populations grow and clinical complexity increases, clinicians will need reliable visibility into how patients are progressing over time,” Caroline Cake, co-founder and CEO of Kneu Health, said in a company press release. “This collaboration with Cedars-Sinai shows that leading academic programs are ready to evolve how chronic neurological disease is managed,” and “is demonstrating that this kind of model can operate within established specialty practice and deliver meaningful clinical impact.”

Parkinson’s is caused by the loss of dopaminergic neurons — nerve cells that produce dopamine, a signaling molecule involved in motor control. This loss leads to motor symptoms such as tremor, slowed movement, and balance and gait problems, as well as nonmotor symptoms including speech and cognitive difficulties.

These symptoms often fluctuate from day to day, making consistent monitoring important for clinicians trying to track disease progression and intervene earlier when needed. However, traditional clinic visits capture symptoms only at specific moments in time and are often spaced several months apart, meaning care adjustments may happen only after symptoms worsen significantly.